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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name mmu-miR-199a-3p
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Mus musculus
Tissues/Cell_line rat retinas
Methods miRNA RT-PCR Array, qRT-PCR
Expression pattern up-regulated
Functional description To verify our array results, we performed qRT-PCR assays on the top 14 most upregulated and all six downregulated miRNAs in total retinas of diabetic rats compared with controls. All 14 of the most upregulated miRNAs were confirmed to be increased in diabetic rats, whereas three of the downregulated miRNAs were confirmed to be decreased in the diabetic retina.
PubMed ID 21498619
Year 2011
Title MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats.
Drug-related ncRNA NO

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